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Abstract: The aim of this paper is to consider the concept of melancholy through Hume’s works. In this regard his "Letter to a Physician" and the Conclusion of Book I of "A Treatise of Human Nature" will be examined. My goal is to present the meaning of melancholy in Hume’s theoretical philosophy, on the one hand, and its meaning in the context of early modern medicine, on the other.
Keywords: melancholy, disease of the learned, humoral theory, causation, skepticism.